According to CoinMeta, following the Federal Reserve's 25-basis-point interest rate hike, the three major U.S. stock indices closed lower on Wednesday: the Dow Jones Industrial Average fell 1.2%, the S&P 500 index dropped 0.44%, and the Nasdaq Composite Index lost 0.01%. Intel rose 4%, while SpaceX increased by 5%. Goldman Sachs and Boeing both fell nearly 4%. In the realm of cryptocurrency-related stocks, MicroStrategy Corporation declined 2.64%, Circle fell 6.77%, Coinbase dropped 4.42%, Sbet fell 4.20%, BMNR fell 3.26%, and Robinhood tumbled 5.46%. This interest rate hike directly tightened market liquidity, increased funding costs, and put pressure on the valuation of risk assets. The market reacted swiftly to the tightening policies, with funds withdrawing from high-risk sectors, leading to a collective decline in U.S. stocks and cryptocurrency-related stocks.